Synthetic approaches, anticancer potential, HSP90 inhibition, multitarget evaluation, molecular modeling and apoptosis mechanistic study of thioquinazolinone skeleton: Promising antibreast cancer agent
Hamed W. El-Shafey, Rania M. Gomaa, Shahenda M. El‐Messery, Fatma E. Goda
Topics & Concepts
ChemistryApoptosisHeLaIC50Cell cycleHsp90Flow cytometryCancer cellCytotoxicityCell cycle checkpointCell cultureHsp90 inhibitorBiochemistryIn vitroMolecular biologyHeat shock proteinCancerBiologyGeneticsGeneHeat shock proteins researchComputational Drug Discovery MethodsBioactive Compounds and Antitumor Agents