Injectable hydrogels of recombinant human collagen type III and chitosan with antibacterial and antioxidative activities for wound healing
Li Xiong, Chen Zhou, Lei Tong, Xiaowen Han, Yaping Zou, Zuqin Dong, Jie Liang, Yafang Chen, Yujiang Fan
Abstract
. Significantly, the rhCol III-CS2 hydrogel increased the deposition of collagen, thereby accelerating full-thickness wound healing. Collectively, this bioinspired hydrogel was a promising multifunctional dressing to reconfigure the damaged tissue without additional drugs, exogenous cytokines, or cells, providing an effective strategy for the repair and regeneration of skin wounds.
Topics & Concepts
ChitosanWound healingSelf-healing hydrogelsRegeneration (biology)Wound dressingRecombinant DNASkin repairBiomedical engineeringMaterials scienceChemistryMedicineSurgeryCell biologyPolymer chemistryBiochemistryComposite materialBiologyGeneWound Healing and TreatmentsElectrospun Nanofibers in Biomedical ApplicationsPeriodontal Regeneration and Treatments