Recalcitrant lichen planus pigmentosus treated with topical ruxolitinib

Abstract

Lichen planus pigmentosum (LPP) is a rare, pigmented variant of lichen planus that is characterized by hyperpigmented, dark brown to gray-black macules in sun-exposed areas of the body such as the face, neck, trunk, and flexures.1 This condition can cause considerable distress and a reduction in quality of life, but there are currently no approved therapies for LPP. Furthermore, existing treatments such as topical and oral steroids, topical calcineurin inhibitors, and topical retinoids, have limited success.

Topics & Concepts