Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy
Grant J. Logan, Mario Mietzsch, Neeta Khandekar, Arlene D’Silva, Daniel G. Anderson, Mawj Mandwie, Jane Hsi, Austin R. Nelson, Paul R. Chipman, Jennifer Jackson, Peter R. Schofield, Daniel Christ, Christopher C. Goodnow, Joanne H. Reed, Michelle A. Farrar, Robert McKenna, Ian E. Alexander
Topics & Concepts
CapsidPolyclonal antibodiesMonoclonal antibodyBiologyAntibodySMA*VirologyGenetic enhancementAdeno-associated virusMolecular biologyVirusGeneImmunologyVector (molecular biology)Recombinant DNAGeneticsCombinatoricsMathematicsNeurogenetic and Muscular Disorders ResearchVirus-based gene therapy researchViral Infections and Immunology Research