Histone demethylase KDM5B licenses macrophage-mediated inflammatory responses by repressing Nfkbia transcription
Yunkai Zhang, Ying Gao, Yuyu Jiang, Yingying Ding, Huiying Chen, Xiang Yan, Zhenzhen Zhan, Xingguang Liu
Topics & Concepts
DemethylaseH3K4me3HistoneCell biologyTranscription factorEpigeneticsChromatinBiologyImmune systemCancer researchRegulation of gene expressionNF-κBChemistrySignal transductionImmunologyGene expressionGeneGeneticsPromoterImmune cells in cancerNF-κB Signaling PathwaysEpigenetics and DNA Methylation