COVID-19 and the kidney
Mohamed Hassanein, Yeshwanter Radhakrishnan, John R. Sedor, Tushar J. Vachharajani, Vidula Vachharajani, Joshua J. Augustine, Sevag Demirjian, George Thomas
Abstract
COVID-19 is primarily considered a respiratory illness, but the kidney may be one of the targets of SARS-CoV-2 infection, since the virus enters cells through the angiotensin-converting enzyme 2 receptor, which is found in abundance in the kidney. Information on kidney involvement in COVID-19 is limited but is evolving rapidly. This article discusses the pathogenesis of acute kidney injury (AKI) in COVID-19, its optimal management, and the impact of COVID-19 on patients with chronic kidney disease, patients with end-stage kidney disease on dialysis, and kidney transplant recipients.
Topics & Concepts
MedicineKidneyKidney diseaseCoronavirus disease 2019 (COVID-19)Acute kidney injuryDialysisPathogenesisArtificial kidneySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ImmunologyIntensive care medicineDiseaseInternal medicineInfectious disease (medical specialty)COVID-19 Clinical Research StudiesCOVID-19 Impact on ReproductionLong-Term Effects of COVID-19