Abnormal mitochondria in Down syndrome iPSC-derived GABAergic interneurons and organoids
Lei Xu, Hai-Qin Huo, Kaiqin Lu, Xiao-Yan Tang, Yuan Hong, Xiao Han, Zixing Fu, Kai-Heng Fang, Min Xu, Xing Guo, Yan Liu
Topics & Concepts
MitochondrionBiologyOrganoidGABAergicCell biologyInduced pluripotent stem cellMitochondrial DNANeuroscienceGeneticsGeneEmbryonic stem cellInhibitory postsynaptic potentialDown syndrome and intellectual disability researchMitochondrial Function and PathologyPluripotent Stem Cells Research