Validation of prostate cancer risk variants rs10993994 and rs7098889 by CRISPR/Cas9 mediated genome editing
Xing Wang, James E. Hayes, Xing Xu, Xiaoni Gao, Dipti Mehta, Hans Lilja, Robert J. Klein
Topics & Concepts
BiologySingle-nucleotide polymorphismGenome-wide association studyGeneticsSNPLinkage disequilibriumTag SNPCRISPRProstate cancerExpression quantitative trait lociGenetic associationSNP genotypingComputational biologyGeneCancerGenotypeCRISPR and Genetic EngineeringRNA Research and SplicingGenetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities