Litcius/Paper detail

Revisiting the role of steroidal therapeutics in the 21st century: an update on FDA approved steroidal drugs (2000–2024)

Ranjit Singh, Ranju Bansal

2025RSC Medicinal Chemistry14 citationsDOIOpen Access PDF

Abstract

successful use of dexamethasone or hydrocortisone during COVID-19 pandemic has renewed the interest in steroidal therapeutics. The present review provides an update on FDA approved steroidal drugs during the years 2000-2024, the status of their clinical studies, the challenges offered by steroidal therapy and the future perspectives to counterbalance all these challenges. Moreover, this review also delivers useful data on the repurposing of steroidal drugs against various diseases along with the novel techniques used for improved steroid delivery.

Topics & Concepts

RepurposingMedicineDrug repositioningPharmacologyDrugEngineeringWaste managementHormonal Regulation and HypertensionHealth Systems, Economic Evaluations, Quality of LifePharmacogenetics and Drug Metabolism