lncRNA H19 facilitates the proliferation and differentiation of human dental pulp stem cells via EZH2-dependent LATS1 methylation
Zhen Du, Xiaoming Shi, Aizhong Guan
Abstract
. Taken together, lncRNA H19 serves as a contributor to the differentiation potential of hDPSCs via the inhibition of LATS1, therefore highlighting novel therapeutic targets for dental pulp repair.
Topics & Concepts
Dental pulp stem cellsCell biologyHippo signaling pathwayStem cellCellular differentiationBiologyCancer researchSignal transductionGeneGeneticsCancer-related molecular mechanisms researchCancer-related gene regulation