Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36
María N. Barrachina, Gerard Pernes, Isabelle C. Becker, Isabelle Allaeys, Thomas I. Hirsch, Dafna J. Groeneveld, Abdullah O. Khan, Daniela Freire, K. Guo, Estelle Carminita, Pooranee K. Morgan, Thomas J. C. Collins, Natalie A. Mellett, Zimu Wei, Ibrahim Almazni, Joseph E. Italiano, James P. Luyendyk, Peter J. Meikle, Mark Puder, Neil V. Morgan, Éric Boilard, Andrew Murphy, Kellie R. Machlus
Topics & Concepts
CD36MegakaryocytePolyunsaturated fatty acidPlateletThrombopoiesisFatty acidLipogenesisBiochemistryBiologyChemistryLipidomeHaematopoiesisCell biologyLipid metabolismImmunologyStem cellReceptorPlatelet Disorders and TreatmentsBlood groups and transfusionSphingolipid Metabolism and Signaling