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In-silico docking, synthesis, structure analysis, DFT calculations, energy frameworks, and pharmacological intervention of [1,3,4]-thiadiazoles analogous as XO inhibitor and on multiple molecular inflammatory targets COX and LOX

Zabiulla Zabiulla, Fares Hezam Al-Ostoot, Hussien Ahmed Khamees, Ashwini Prasad, Farhan Zameer, Shaukath Ara Khanum

2022Journal of Molecular Structure17 citationsDOI

Topics & Concepts

ChemistryXanthine oxidasePharmacologyUric acidFebuxostatGoutHyperuricemiaAllopurinolAndrographolideBiochemistryEnzymeInternal medicineMedicineSynthesis and biological activityGout, Hyperuricemia, Uric AcidSynthesis and Reactions of Organic Compounds
In-silico docking, synthesis, structure analysis, DFT calculations, energy frameworks, and pharmacological intervention of [1,3,4]-thiadiazoles analogous as XO inhibitor and on multiple molecular inflammatory targets COX and LOX | Litcius