Mitochondrial DNA stress primes the antiviral innate immune response
A. Phillip West, William Khoury-Hanold, Matthew Staron, Michal Caspi Tal, Cristiana M. Pineda, Sabine M. Lang, Megan Bestwick, Brett A. Duguay, Nuno Raimundo, Donna A. MacDuff, Susan M. Kaech, James R. Smiley, Robert E. Means, Akiko Iwasaki, Gerald S. Shadel
Topics & Concepts
IRF3BiologyTFAMMitochondrial DNAInterferonInnate immune systemCell biologyMitochondrionIntegrated stress responseStimulator of interferon genesInterferon type IGeneticsImmune systemGeneTranslation (biology)Messenger RNAinterferon and immune responsesInflammasome and immune disordersImmune Response and Inflammation