Physiopathology of Lifestyle Interventions in Non-Alcoholic Fatty Liver Disease (NAFLD)
David Carneros, Guillermo López‐Lluch, Matilde Bustos
Abstract
Non-alcoholic fatty liver disease (NAFLD) is a major health problem, and its prevalence has increased in recent years. Diet and exercise interventions are the first-line treatment options, with weight loss via a hypocaloric diet being the most important therapeutic target in NAFLD. However, most NAFLD patients are not able to achieve such weight loss. Therefore, the requisite is the investigation of other effective therapeutic approaches. This review summarizes research on understanding complex pathophysiology underlying dietary approaches and exercise interventions with the potential to prevent and treat NAFLD.
Topics & Concepts
Fatty liverMedicineWeight lossPathophysiologyDiseasePsychological interventionInternal medicineIntensive care medicineGastroenterologyObesityBioinformaticsPsychiatryBiologyLiver Disease Diagnosis and TreatmentDiet, Metabolism, and DiseaseDiet and metabolism studies