Enforced expression of Runx3 improved CAR-T cell potency in solid tumor via enhancing resistance to activation-induced cell death
Yi Wang, Honghong Zhang, Guoxiu Du, Hong Luo, Su Jingwen, Yansha Sun, Min Zhou, Bizhi Shi, Henry Q.X. Li, Hua Jiang, Zonghai Li
Topics & Concepts
Chimeric antigen receptorProinflammatory cytokineCytotoxic T cellT cellTumor necrosis factor alphaCancer researchBiologyCell biologyImmunologyImmune systemIn vitroInflammationBiochemistryCAR-T cell therapy researchImmune Cell Function and InteractionViral Infectious Diseases and Gene Expression in Insects