Dibenzocyclooctadiene lignans from Kadsura coccinea alleviate APAP-induced hepatotoxicity via oxidative stress inhibition and activating the Nrf2 pathway in vitro
Yupei Yang, Yuqing Jian, Shaowu Cheng, Yanzhe Jia, Yongbei Liu, Huanghe Yu, Liang Cao, Bin Li, Caiyun Peng, M. Iqbal Choudhary, Atta‐ur Rahman, Wei Wang
Topics & Concepts
ChemistryPhytochemicalHepatoprotectionOxidative stressIn vitroStereochemistryLignanPharmacologyBiochemistryEnzymeBiologyGlutathioneDrug-Induced Hepatotoxicity and ProtectionPlant-derived Lignans Synthesis and BioactivityChemotherapy-induced organ toxicity mitigation