Effects of type 1 diabetes on reflexive cardiovascular responses to intermittent muscle contraction
Ann‐Katrin Grotle, Yu Huo, Michelle Harrison, Junghoon Lee, Kai M. Ybarbo, Audrey J. Stone
2020American Journal of Physiology-Regulatory, Integrative and Comparative Physiology10 citationsDOI
Abstract
This is the first study to provide evidence that early-stage type 1 diabetes mellitus (T1DM) leads to an exaggerated exercise pressor reflex evoked by intermittent muscle contraction, resulting in substantially higher cardiovascular strain. These findings are significant as they indicate that interventions targeting the exercise pressor reflex may work to alleviate the increased cardiovascular strain and overall burden during exercise in T1DM.
Topics & Concepts
ReflexContraction (grammar)MedicineType 1 diabetesInternal medicineDiabetes mellitusMuscle contractionCardiologyEndocrinologyHeart Rate Variability and Autonomic ControlCardiovascular and exercise physiologyCardiovascular Syncope and Autonomic Disorders