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Natural soluble epoxide hydrolase inhibitors from Inula britanica and their potential interactions with soluble epoxide hydrolase: Insight from inhibition kinetics and molecular dynamics

Wen‐Yu Zhao, Juanjuan Yan, Min Zhang, Chao Wang, Lei Feng, Xia Lv, Xiaokui Huo, Cheng‐Peng Sun, Li-Xia Chen, Xiaochi Ma

2021Chemico-Biological Interactions27 citationsDOI

Topics & Concepts

Epoxide hydrolase 2ChemistryStereochemistryPhytochemicalEnantiomerDocking (animal)Circular dichroismMixed inhibitionIC50Non-competitive inhibitionEnzymeBiochemistryIn vitroNursingMedicineEicosanoids and Hypertension PharmacologyFree Radicals and AntioxidantsPharmacogenetics and Drug Metabolism
Natural soluble epoxide hydrolase inhibitors from Inula britanica and their potential interactions with soluble epoxide hydrolase: Insight from inhibition kinetics and molecular dynamics | Litcius