Light-Activated CO Donor as a Universal CO Surrogate for Pd-Catalyzed and Light-Mediated Carbonylation
Ladie Kimberly De La Cruz, Nicola Bauer, Alyssa Cachuela, Wing Sze Tam, Ravi Tripathi, Xiaoxiao Yang, Binghe Wang
Abstract
A low-molecular-weight, solid CO surrogate that only requires a low-power LED for activation to release 2 equiv of CO is reported. The surrogate can be universally implemented in various palladium-catalyzed carbonylative transformations. It is also compatible with protocols that employ blue-light to activate conventionally inaccessible substrates such as nonactivated alkyl halides. Furthermore, we demonstrate that the photolabile CO-releasing scaffold can be installed into polymeric materials, thereby creating new materials with CO-releasing capabilities.
Topics & Concepts
CarbonylationChemistryCatalysisHalidePalladiumAlkylCombinatorial chemistryPhotochemistryOrganic chemistryCarbon monoxideCarbon dioxide utilization in catalysisCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization Methods