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A review on current diagnostic techniques for COVID-19

Islam El Jaddaoui, Malika Allali, Sanae Raoui, Sofia Sehli, Nihal Habib, Bouchra Chaouni, Najib Al Idrissi, Najwa Benslima, Wissal Maher, Houda Benrahma, Noureddine Hamamouch, Kamal El Bissati, Sahar El Kasmi, Salsabil Hamdi, Youssef Bakri, Chakib Nejjari, Saaïd Amzazi, Hassan Ghazal

2021Expert Review of Molecular Diagnostics32 citationsDOI

Abstract

INTRODUCTION: SARS-Cov-2 first appeared in Wuhan, China, in December 2019 and spread all over the world soon after that. Given the infectious nature ofSARS-CoV-2, fast and accurate diagnosis tools are important to detect the virus. In this review, we discuss the different diagnostic tests that are currently being implemented in laboratories and provide a description of various COVID-19 kits. AREAS COVERED: We summarize molecular techniques that target the viral load, serological methods used for SARS-CoV-2 specific antibodies detection as well as newly developed faster assays for the detection of SARS-COV 2 in various biological samples. EXPERT OPINION: In the light of the widespread pandemic, the massive diagnosis of COVID-19, using various detection techniques, appears to be the most effective strategy for monitoring and containing its propagation.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakVirologyDiagnostic testPandemicMolecular diagnosticsMedicineIntensive care medicineComputer scienceInfectious disease (medical specialty)BiologyPathologyBioinformaticsOutbreakDiseaseVeterinary medicineSARS-CoV-2 detection and testingBiosensors and Analytical DetectionSARS-CoV-2 and COVID-19 Research