Acute kidney injury in SARS-CoV-2 infected patients
Vito Fanelli, Marco Fiorentino, Vincenzo Cantaluppi, Loreto Gesualdo, Giovanni Stallone, Claudio Ronco, Giuseppe Castellano
Abstract
Severe acute respiratory syndrome coronavirus-2 (SARSCoV-2) is the pathogen responsible of atypical pneumonia that has affected more than 330,000 people and caused death of more than 14,000 patients (as of March 23, 2020, WHO Report). Coronavirus spike (S) glycoproteins mediate entry into cells end predominantly lung epithelial alveolar cells precipitating an interstitial pneumonia that evolves through acute respiratory distress syndrome (ARDS) [1].
Topics & Concepts
MedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Acute kidney injuryCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakSars virusEmergency medicineBetacoronavirusIntensive care medicinePandemicCoronavirus InfectionsVirologyMedical emergencyInternal medicineOutbreakInfectious disease (medical specialty)DiseaseAcute Kidney Injury ResearchMuscle and Compartmental DisordersCardiac Arrest and Resuscitation