Antibacterial activity of Syzygium aromaticum (clove) against uropathogens producing ESBL, MBL, and AmpC beta-lactamase: Are we close to getting a new antibacterial agent?
Dakshina Bisht, SameerS Faujdar, Amisha Sharma
Abstract
INTRODUCTION: ) against extended-spectrum beta-lactamase (ESBL), metallo-beta-lactamase (MBL), and AmpC beta-lactamase-producing gram-negative bacteria causing urinary tract infection. METHODS: ) for its antibacterial activity. RESULTS: species with 19 mm zone of inhibition, 0.39 mg/ml minimum inhibitory concentration (MIC) and 0.19 mg/ml minimum bactericidal concentration (MBC). CONCLUSIONS: Clove extract showed different antibacterial potential against all gram-negative uropathogens. Clove activity for particular strain was found to be similar between isolates producing beta-lactamase and non beta-lactamase.
Topics & Concepts
SyzygiumAntibacterial activityBeta-lactamaseMicrobiologyGramProteusMedicineMinimum inhibitory concentrationBacteriaTraditional medicineAntibioticsBiologyEscherichia coliBiochemistryGeneticsGeneEssential Oils and Antimicrobial ActivityPhytochemistry and Biological ActivitiesMoringa oleifera research and applications