Guanosine-rich aptamers@Cu<sub>2</sub>O nanoparticles: enhanced peroxidase activity and specific recognition capability at neutral pH
Hongchao Ma, Lan Wang, Yifan Li, Yanhui Wei
Abstract
The decoration of Cu2O nanoparticles with guanosine-rich aptamers can significantly enhance their peroxidase activity at neutral pH and endow them with specific recognition capabilities. Both the phosphate backbone and guanine of the aptamers contribute to the enhancement. The excellent enzyme-like properties of this Cu2O-aptamer system make it a versatile platform for the development of neutral pH biosensors.
Topics & Concepts
AptamerPeroxidaseGuanosineChemistryCombinatorial chemistryNanoparticleNanotechnologyMaterials scienceBiochemistryEnzymeBiologyMolecular biologyAdvanced Nanomaterials in CatalysisAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection