Bone Tuberculous Granulomatous Inflammation Mimicking Malignancy on 68Ga-FAPI PET/CT
Weidong Gong, Xiao Yang, Chunru Mou, Huipan Liu, Chunyin Zhang
Abstract
ABSTRACT: A 50-year-old woman presented with back pain for 1 month. Chest CT showed osteolytic destruction of T6 vertebral body. A malignancy was suspected. The patient was subsequently enrolled in the clinical trial of 68Ga-FAPI PET/CT. 68Ga-FAPI PET/CT revealed multiple bone destruction with increased FAPI activity. It was also highly suggestive of malignancy or metastases. However, pathological examination after T6 vertebral surgery confirmed the diagnosis of tuberculous granulomatous inflammation.
Topics & Concepts
MedicineMalignancyPathologicalPathologyTuberculosisBack painGranulomatous inflammationHistopathological examinationInflammationRadiologyGranulomaPhysical examinationChest painBone painVertebral bodyPeptidase Inhibition and AnalysisOrthopedic Infections and TreatmentsConnective tissue disorders research