NAD+ Regeneration Rescues Lifespan, but Not Ataxia, in a Mouse Model of Brain Mitochondrial Complex I Dysfunction
Gregory S. McElroy, Colleen R. Reczek, Paul A. Reyfman, Divakar S. Mithal, Craig Horbinski, Navdeep S. Chandel
Topics & Concepts
AtaxiaNAD+ kinaseRegeneration (biology)MitochondrionNeuroscienceCell biologyBiologyGeneticsMedicineBiochemistryEnzymeMitochondrial Function and PathologySirtuins and Resveratrol in MedicineTryptophan and brain disorders