A mechanistic review of Parkin activation
Mehmet Gundogdu, Roya Tadayon, Giulia Salzano, Gary S. Shaw, Helen Walden
Topics & Concepts
ParkinPINK1MitophagyUbiquitin ligaseUbiquitinTensinCell biologyPTENKinaseBiologyAutophagyChemistryGeneticsSignal transductionParkinson's diseasePI3K/AKT/mTOR pathwayMedicineInternal medicineApoptosisDiseaseGeneAutophagy in Disease and TherapyUbiquitin and proteasome pathwaysParkinson's Disease Mechanisms and Treatments