Immune-responsive gene 1 protects against liver injury caused by concanavalin A via the activation Nrf2/HO-1 pathway and inhibition of ROS activation pathways
Wenchang Yang, Yaxin Wang, Peng Zhang, Xiong Sun, Xin Chen, Jiaxian Yu, Liang Shi, Yuping Yin, Kaixiong Tao, Ruidong Li
Topics & Concepts
PyroptosisInflammasomeApoptosisPyrin domainHepatocyteLiver injuryIn vivoReactive oxygen speciesChemistryConcanavalin APharmacologyCell biologyBiologyReceptorBiochemistryIn vitroBiotechnologyInflammasome and immune disordersDrug-Induced Hepatotoxicity and ProtectionImmune cells in cancer