Gamabufotalin suppressed osteosarcoma stem cells through the TGF-β/periostin/PI3K/AKT pathway
Kun Ma, Chuan Zhang, Wuyin Li
Topics & Concepts
PeriostinPI3K/AKT/mTOR pathwayProtein kinase BHomeobox protein NANOGChemistryCancer researchMolecular biologyViability assayMTT assaySOX2Epithelial–mesenchymal transitionCell growthBiologyMetastasisSignal transductionCellCell biologyEmbryonic stem cellExtracellular matrixCancerInduced pluripotent stem cellGeneticsGeneBiochemistryCardiac Fibrosis and RemodelingProtease and Inhibitor MechanismsTGF-β signaling in diseases