Recent Advances in Organocatalytic Enantioselective Reactions of α‐Functionalized Propargylic Alcohols
Yan Xia, Meiwen Liu, Wen‐Jun Li, Pengfei Li, Pengfei Li
Abstract
Abstract Owing to their unique properties, propargylic alcohols have been recognized as one of the most attractive synthons in the field of organic synthesis. Particularly, with the aid of auxiliary group, the α‐functionalized propargylic alcohols have been frequently involved in the organocatalytic enantioselective substitutions, conjugate additions, annulations and related reactions in recent years. Accordingly, the present review highlights recent advancements in the application of α‐functionalized propargylic alcohols in the field of asymmetric organocatalysis, which is organized according to the type of auxiliary group.
Topics & Concepts
Enantioselective synthesisChemistryOrganocatalysisOrganic chemistryCombinatorial chemistryCatalysisAsymmetric Synthesis and CatalysisCatalytic Alkyne ReactionsSynthetic Organic Chemistry Methods