Transcriptionally amplified synthesis of fluorogenic RNA aptamers for label-free DNA glycosylase assay
Fei Ma, Ya-Zhen Liu, Meng Liu, Jian‐Ge Qiu, Chun‐yang Zhang
Abstract
. Moreover, it can be applied for screening UDG inhibitors and measuring endogenous UDG activity in different cells.
Topics & Concepts
Uracil-DNA glycosylaseAptamerDNA glycosylaseDNAChemistryRNAUracilDetection limitMolecular biologyTranscription (linguistics)EndogenyBiochemistryCombinatorial chemistryGeneChromatographyBiologyDNA repairPhilosophyLinguisticsAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms