Discovery of novel inhibitors of dengue viral RNA-dependent RNA polymerase by molecular docking, in vitro assay, DFT, and MD simulations
Chaochun Wei, Keli Zong, Wei Li, Xu Zhao, Jiajun Ruan, Susu Zhang, Jinɡjinɡ Li, Xiaojing Liu, Hong Yan, Ruiyuan Cao, Xingzhou Li
Topics & Concepts
Dengue feverIn vitroPolymeraseVirologyDengue virusChemistryDocking (animal)RNA-dependent RNA polymeraseRNA polymeraseRNABiologyEnzymeBiochemistryMedicineGeneNursingMosquito-borne diseases and controlHIV Research and TreatmentViral Infections and Outbreaks Research