Role of Vaginal Microbiota Dysbiosis in Gynecological Diseases and the Potential Interventions
Yiwen Han, Zhaoxia Liu, Tingtao Chen
Abstract
dominance and increase of microbial diversity, is closely related to gynecological diseases; thus, intervention on microbiota composition is significant and promising in the treatment of gynecological diseases. Currently, antibiotics and/or probiotics are the mainstay of treatment, which show favorable therapeutic effects but also bring problems such as drug resistance and high recurrence. In this review, we discuss the role of vaginal microbiota dysbiosis in various gynecological infectious and non-infectious diseases, as well as the current and potential interventions.
Topics & Concepts
DysbiosisLactobacillusAntibioticsMedicineColonisation resistanceDominance (genetics)Psychological interventionImmunologyBiologyGut floraMicrobiologyBacteriaBiochemistryGeneticsGenePsychiatryReproductive tract infections researchGenital Health and DiseaseUrinary Tract Infections Management