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[Corrigendum] Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes

Yubiao Zhang, Weisong Cai, Guangtao Han, Siqi Zhou, Jianping Li, Chen Mao, Haohuan Li

2020International Journal of Molecular Medicine28 citationsDOIOpen Access PDF

Abstract

Following the publication of the above article, the authors have realized that the first author, who analyzed the data, inadvertently made a mistake by over‑estimating the background of the blots in calculating the intensity of the histograms for the western blots shown in Fig. 6A and E. This error led to subsequent differences in the actual quantification and statistics from the originally submitted results. Accordingly, to further verify the conclusions reported in the study, the authors repeated these experiments independently, and the results were found to be consistent with the same changes in trends as originally observed. The revised version of Fig. 6, containing the new western blot data for Fig. 6A and E and new histograms showing the quantification of these data, is shown on the next page. The authors are grateful to the Editor of International Journal of Molecular Medicine for allowing them the opportunity to publish this Corrigendum, and apologize to the readership for any inconvenience caused. [the original article was published in International Journal of Molecular Medicine 45: 1225-1236, 2020; DOI: 10.3892/ijmm.2020.4491].

Topics & Concepts

Panax notoginsengPI3K/AKT/mTOR pathwayApoptosisProtein kinase BOncogeneCell cycleSenescenceCancer researchMedicineBiologyChemistryTraditional medicineCell biologyPathologyBiochemistryAlternative medicineGinseng Biological Effects and ApplicationsPharmacological Effects of Natural CompoundsMedicinal Plant Pharmacodynamics Research
[Corrigendum] Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes | Litcius