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Bronchoscopic interventions for severe emphysema: Where are we now?

Pallav L. Shah, Dirk‐Jan Slebos

2020Respirology36 citationsDOIOpen Access PDF

Abstract

Patients with severe emphysema have limited treatment options and only derive a small benefit from optimal medical treatment. The only other therapy to have significant clinical beneficial effect in emphysema is LVRS but the perceived risk and invasiveness of surgery has fuelled bronchoscopic approaches to induce lung volume reduction. There are multiple bronchoscopic methods for achieving volume reduction in severe emphysema: EBV, airway bypass procedure, endobronchial coils, thermal (vapour) sclerosis and chemical sclerosis (sealants). Optimal patient selection is key to successful patient outcomes. This review discusses bronchoscopic approaches for emphysema treatment which has progressed through clinical trials to clinical practice.

Topics & Concepts

MedicineLung volume reduction surgeryBronchoscopyClinical trialClinical PracticeIntensive care medicineAirwaySurgeryLungLung volumesInternal medicinePhysical therapyChronic Obstructive Pulmonary Disease (COPD) ResearchRespiratory Support and MechanismsPleural and Pulmonary Diseases