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3D Electron Diffraction for Chemical Analysis: Instrumentation Developments and Innovative Applications

Tim Gruene, Enrico Mugnaioli

2021Chemical Reviews89 citationsDOIOpen Access PDF

Abstract

In the past few years, many exciting papers reported results based on crystal structure determination by electron diffraction. The aim of this review is to provide general and practical information to structural chemists interested in stepping into this emerging field. We discuss technical characteristics of electron microscopes for research units that would like to acquire their own instrumentation, as well as those practical aspects that appear different between X-ray and electron crystallography. We also include a discussion about applications where electron crystallography provides information that is different, and possibly complementary, with respect to what is available from X-ray crystallography.

Topics & Concepts

Electron crystallographyInstrumentation (computer programming)ChemistryElectron diffractionNanotechnologyDiffractionElectronField (mathematics)Electron microscopeCrystallographyEngineering physicsComputer scienceOpticsPhysicsMaterials scienceOperating systemPure mathematicsQuantum mechanicsMathematicsX-ray Diffraction in CrystallographyEnzyme Structure and FunctionElectron and X-Ray Spectroscopy Techniques
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