A distinct cytokine network distinguishes chimeric antigen receptor T cell (CAR-T)–associated hemophagocytic lymphohistiocytosis-like toxicity (carHLH) from severe cytokine release syndrome following CAR-T therapy
Cheng Zu, Shenghao Wu, Mingming Zhang, Guoqing Wei, Huijun Xu, Jiazhen Cui, Alex H. Chang, He Huang, Yongxian Hu
Topics & Concepts
Chimeric antigen receptorCytokine release syndromeImmunologyHemophagocytic lymphohistiocytosisCytokineMedicineGranzyme BAntigenT cellInterleukinCD8Immune systemInternal medicineDiseaseCAR-T cell therapy researchAutoimmune and Inflammatory Disorders ResearchCutaneous lymphoproliferative disorders research