Litcius/Paper detail

The use of metronidazole in acute diarrhea in dogs: a narrative review

Connor Ellis, Adesola Odunayo, M. Katherine Tolbert

2023Topics in companion animal medicine17 citationsDOIOpen Access PDF

Abstract

Acute diarrhea is a common reason for non-wellness veterinary visits in dogs. Treatment for acute diarrhea usually consists of supportive care with nutritional intervention, fluid therapy, anthelmintics, and often an antibiotic - commonly metronidazole in North America. The empirical use of metronidazole for acute diarrhea in dogs has been a common practice in veterinary medicine for many decades; however, recent studies evaluating its use suggest it may be inappropriately utilized in many cases. Herein, we review the evidence evaluating the use of metronidazole and other antibiotics in acute diarrhea in the human and veterinary literature. Recommendations on the use of metronidazole and other antibiotics as well as other therapeutic considerations in the treatment of acute diarrhea are also provided.

Topics & Concepts

MetronidazoleMedicineDiarrheaAcute diarrheaAntibioticsIntensive care medicineNarrative reviewInternal medicineMicrobiologyBiologyViral gastroenteritis research and epidemiologyClostridium difficile and Clostridium perfringens researchVeterinary Oncology Research