Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
Ke Xu, Na Yin, Min Peng, Efstathios G. Stamatiades, Sagar Chhangawala, Amy Shyu, Peng Li, Xian Zhang, H. Mytrang, Kristelle J. Capistrano, Chun Chou, Christina S. Leslie, Ming O. Li
Topics & Concepts
Warburg effectFOXO1GlycolysisLactate dehydrogenase AAnaerobic glycolysisBiologyPI3K/AKT/mTOR pathwayCell biologyProtein kinase BEffectorCell growthNAD+ kinaseKinaseSignal transductionBiochemistryMetabolismEnzymeAutophagy in Disease and TherapyImmune Cell Function and InteractionCAR-T cell therapy research