Rapid quantification of vincristine in mouse plasma using ESI-LC-MS/MS: Application to pharmacokinetic studies
Yan Jin, Yang Li, Muhammad Erfan Uddin, Alex Sparreboom, Shuiying Hu
Topics & Concepts
PharmacokineticsVincristineChemistryChromatographyExtraction (chemistry)Selected reaction monitoringDetection limitCalibration curvePharmacologyMass spectrometryTandem mass spectrometryChemotherapyCyclophosphamideSurgeryMedicineCancer Treatment and PharmacologyCancer therapeutics and mechanismsBerberine and alkaloids research