A natural flavonoid, apigenin isolated from Clerodendrum viscosum leaves, induces G2/M phase cell cycle arrest and apoptosis in MCF-7 cells through the regulation of p53 and caspase-cascade pathway
Anil Khushalrao Shendge, Dipankar Chaudhuri, Tapasree Basu, Nripendranath Mandal
Topics & Concepts
ApigeninApoptosisProgrammed cell deathCell cycleCell cycle checkpointViability assayIntracellularFragmentation (computing)DNA fragmentationCaspaseCytotoxicityMCF-7Poly ADP ribose polymeraseMedicineBiologyCancer cellCell biologyFlavonoidBiochemistryIn vitroCancerInternal medicineGenePolymeraseEcologyHuman breastAntioxidantFlavonoids in Medical ResearchSilymarin and Mushroom PoisoningTannin, Tannase and Anticancer Activities