Adiponectin receptor 1 variants contribute to hypertrophic cardiomyopathy that can be reversed by rapamycin
Perundurai S. Dhandapany, Soojeong Kang, Deepak Kashyap, Raksha Rajagopal, Nagalingam R. Sundaresan, Rajvir Singh, Kumarasamy Thangaraj, Shilpa Jayaprakash, Cholenahally Nanjappa Manjunath, Jayaprakash Shenthar, Djamel Lebeche
Abstract
Gene variants in adiponectin receptor 1 cause pathological enlarged hearts.
Topics & Concepts
Hypertrophic cardiomyopathyAdiponectinPathologicalAdiponectin receptor 1ReceptorInternal medicineEndocrinologyBiologyCardiomyopathyGeneMedicineHeart failureGeneticsInsulin resistanceInsulinAdipokines, Inflammation, and Metabolic DiseasesCardiomyopathy and Myosin StudiesCardiovascular Disease and Adiposity