Litcius/Paper detail

Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients

Li-Kun Zhou, Zhen Zhou, Xia-Ming Jiang, Yishan Zheng, Xi Chen, Zheng Fu, Gengfu Xiao, Chen-Yu Zhang, Leike Zhang, Yongxiang Yi

2020Cell Discovery163 citationsDOIOpen Access PDF

Abstract

The Coronavirus disease 2019 (COVID-19) pandemic is one of the most serious global public health crises to date. As of July 12, 2020, more than 12.6 million cases of COVID-19 infection with 0.56 million deaths were confirmed worldwide 1 . Since there are no effective therapeutics to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, the causative virus of COVID-19) infection so far, the pandemic is rapidly spreading worldwide. It is urgent to develop effective therapies, not only to treat infected patients but also to control the pandemic.

Topics & Concepts

HoneysucklePandemicDecoctionVirologyCoronavirusInfluenza A virus subtype H5N1Coronavirus disease 2019 (COVID-19)MedicineViral replicationInfluenza A virusVirusSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)BiologyDiseaseTraditional medicineInternal medicineInfectious disease (medical specialty)Traditional Chinese medicinePathologyAlternative medicineMicroRNA in disease regulationSirtuins and Resveratrol in MedicineCircular RNAs in diseases