Abnormal intestinal milieu in posttraumatic stress disorder is not impacted by treatment that improves symptoms
Robin M. Voigt, Alyson K. Zalta, Shohreh Raeisi, Lijuan Zhang, J. Mark Brown, Christopher B. Forsyth, Randy A. Boley, Philip Held, Mark H. Pollack, Ali Keshavarzian
2022American Journal of Physiology-Gastrointestinal and Liver Physiology26 citationsDOIOpen Access PDF
Abstract
This study confirms an abnormal intestinal environment is present in subjects with PTSD. This study adds to what is already known by examining the intestinal barrier and evaluating the relationship between intestinal readouts and PTSD symptoms and is the first to report the impact of PTSD treatment (which improves symptoms) on intestinal readouts. This study suggests that targeting the intestine as an adjunct approach could improve the treatment of PTSD.
Topics & Concepts
Cognitive processing therapyPosttraumatic stressPsychological interventionExposure therapyPsychiatryPsychologyClinical psychologyCognitionCognitive behavioral therapyMedicineAnxietyIntensive Care Unit Cognitive DisordersStress Responses and CortisolPosttraumatic Stress Disorder Research