Litcius/Paper detail

AARS1 and AARS2 sense l-lactate to regulate cGAS as global lysine lactyltransferases

Heyu Li, Chao Liu, Ran Li, Lili Zhou, Yu Ran, Qiqing Yang, Huizhe Huang, Huasong Lu, Hai Song, Bing Yang, Heng Ru, Shixian Lin, Long Zhang

2024Nature311 citationsDOI

Topics & Concepts

LysineSense (electronics)ChemistryBiochemistryCell biologyBiologyAmino acidPhysical chemistryinterferon and immune responsesRNA modifications and cancerUbiquitin and proteasome pathways