Litcius/Paper detail

Emerging coronaviruses: Genome structure, replication, and pathogenesis

Yu Chen, Qianyun Liu, Deyin Guo

2020Journal of Medical Virology3,157 citationsDOIOpen Access PDF

Abstract

The recent emergence of a novel coronavirus (2019-nCoV), which is causing an outbreak of unusual viral pneumonia in patients in Wuhan, a central city in China, is another warning of the risk of CoVs posed to public health. In this minireview, we provide a brief introduction of the general features of CoVs and describe diseases caused by different CoVs in humans and animals. This review will help understand the biology and potential risk of CoVs that exist in richness in wildlife such as bats.

Topics & Concepts

CoronavirusBiologyVirologyOutbreakCoronavirus disease 2019 (COVID-19)GenomeSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pandemic2019-20 coronavirus outbreakPneumoniaBetacoronavirusComputational biologyGeneticsGeneGeographyMedicineDiseaseInfectious disease (medical specialty)ArchaeologyPathologySARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections StudiesViral gastroenteritis research and epidemiology