Research and Application of Medical Polyetheretherketone as Bone Repair Material
Feifei Pu, Yihan Yu, Z. Zhang, Wei Wu, Zengwu Shao, Chao Li, Jing Feng, Longjian Xue, Fengxia Chen
Abstract
Polyetheretherketone (PEEK) can potentially be used for bone repair because its elastic modulus is similar to that of human natural bone and good biocompatibility and chemical stability. However, its hydrophobicity and biological inertness limit its application in the biomedical field. Inspired by the composition, structure, and function of bone tissue, many strategies are proposed to change the structure and functionality of the PEEK surface. In this review, the applications of PEEK in bone repair and the optimization strategy for PEEK's biological activity are reviewed, which provides a direction for the development of multifunctional bone repair materials in the future.