Litcius/Paper detail

Identification of 2-hydroxybenzoic acid derivatives as selective SIRT5 inhibitors

Yanghan Liu, Bikash Debnath, Surinder Kumar, David B. Lombard, Nouri Neamati

2022European Journal of Medicinal Chemistry10 citationsDOIOpen Access PDF

Topics & Concepts

ChemistrySirtuinLead compoundBiochemistryEnzymePotencyHigh-throughput screeningCarboxylic acidCombinatorial chemistryStereochemistryIn vitroNAD+ kinaseSirtuins and Resveratrol in MedicineCalcium signaling and nucleotide metabolismTea Polyphenols and Effects