Elevated intracellular cAMP concentration mediates growth suppression in glioma cells
Dewi Safitri, Matthew Harris, H. Phelps Potter, Ho Yan Yeung, Ian J. Winfield, Liliya Kopanitsa, Fredrik Svensson, Taufiq Rahman, Matthew T. Harper, David Bailey, Graham Ladds
Topics & Concepts
ForskolinIntracellularAdenylyl cyclaseActivator (genetics)PhosphodiesteraseCell growthCell biologyGliomaChemistryCell cyclecAMP-dependent pathwayPhosphodiesterase 3CellBiologyCancer researchSignal transductionBiochemistryIn vitroEnzymeReceptorPhosphodiesterase function and regulationReceptor Mechanisms and SignalingSynthesis and Catalytic Reactions