FOXK2 transcriptionally activating VEGFA induces apatinib resistance in anaplastic thyroid cancer through VEGFA/VEGFR1 pathway
Haoran Feng, Zhijian Jin, Juyong Liang, Qiwu Zhao, Ling Zhan, Zheyu Yang, Jiqi Yan, Jie Kuang, Xi Cheng, Weihua Qiu
Topics & Concepts
Vascular endothelial growth factor AAngiogenesisCancer researchBiologyChromatin immunoprecipitationMAPK/ERK pathwayProtein kinase BThyroid cancerTranscription factorAnaplastic thyroid cancerVascular endothelial growth factorSignal transductionCancerCell biologyGene expressionPromoterGeneticsVEGF receptorsGeneThyroid Cancer Diagnosis and TreatmentEstrogen and related hormone effectsEndometriosis Research and Treatment