Both selenium deficiency and excess impair male reproductive system via inducing oxidative stress-activated PI3K/AKT-mediated apoptosis and cell proliferation signaling in testis of mice
Zijian Xu, Meng Liu, Qin-Jian Niu, Yuxuan Huang, Ling Zhao, Xin Gen Lei, Lv‐Hui Sun
Topics & Concepts
Oxidative stressSpermatogenesisProtein kinase BApoptosisEndocrinologyInternal medicineSpermPI3K/AKT/mTOR pathwayAndrologyBiologysedSperm motilityReactive oxygen speciesSignal transductionCell biologyMedicineGeneticsSelenium in Biological SystemsSperm and Testicular FunctionMale Reproductive Health Studies